Vasoactive agent Picamilon in pigmented retinal abiotrophy

Davydova GA, Mukha AI

[Article in Russian]

Otdel Patologii Setchatki, 
Mosk. NI Institut Glaznykh Boleznej, 
Minzdravmedproma Rossii, Moskva Russian Federation 
Vestnik Oftalmologii (Russian Federation), 1995, 111/3 (20-22) 

Abstract

Eighty patients with pigmented retinal abiotrophy (PRA) and 20 controls were examined.  The perfusion pressure and arteriovenous coefficient are markedly reduced in patients with stages 1-2 PRA, in comparison with controls.  Deterioration of the visual function in patients with stages 3-4 PRA vs. that in stages 1-2 was associated with a more marked reduction of the hemodynamic parameters and the status of ocular vessels.  Picamilon therapy in a dose of 2 ml of 10% solution once a day intramuscularly for 10 days led to improvement of the visual function and ocular hemodynamics in patients with PRA. Treatment efficacy was higher in patients with disease stages 1-2.  Picamilon is recommended for the treatment of patients with PRA.

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